Association of resection type, nodal evaluation, and survival in early-stage lung squamous cell carcinoma

Evelyn Alexander, Titilope Sandra Saheed, Ahmed Elkamel, Shamele Battan-Wraith, Chiu-Hsieh Hsu, Jonathan Rice, Stephanie Worrell, Praveen Sridhar · 2026

Read Association of resection type, nodal evaluation, and survival in early-stage lung squamous cell carcinoma by Evelyn Alexander, Titilope Sandra Saheed, Ahmed Elkamel, Shamele Battan-Wraith, Chiu-Hsieh Hsu, Jonathan Rice, Stephanie Worrell, Praveen Sridhar (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13559343.txt.

Description

Evelyn Alexander and colleagues compare two extents of lung removal for early-stage squamous cell carcinoma, asking whether taking less lung costs patients survival. Their 2026 study drew on the National Cancer Database for 2010 through 2022 and found 207 adults with stage IA disease. About 63 percent had a lobectomy, while the rest had a smaller sublobar resection.

Patients with sublobar resection were somewhat older, and surgeons examined far fewer lymph nodes in their cases, a median of one against nine for lobectomy. Survival looked worse after the smaller operation before full adjustment. Once lymph node evaluation entered the model, however, the gap shrank and lost statistical significance. The authors read the result as a warning that node checking matters whatever the resection size. They label the findings hypothesis-generating and call for prospective, histology-specific study.

Catalog record

CREATOREvelyn Alexander, Titilope Sandra Saheed, Ahmed Elkamel, Shamele Battan-Wraith, Chiu-Hsieh Hsu, Jonathan Rice, Stephanie Worrell, Praveen Sridhar
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE30 KB
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13559343

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