Temporal trends in small-cell lung cancer trials registered on ClinicalTrials.gov: a cross-sectional analysis (1996–2025)
Jian Cui, Jianhua Chen, Hongming Zhang · 2026
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Description
Jian Cui, Jianhua Chen, and Hongming Zhang charted how small-cell lung cancer trials changed over three decades in a 2026 analysis. They screened every interventional trial for this cancer registered on ClinicalTrials.gov with a start date between 1996 and 2025. Two oncologists checked each record against set rules, with a third settling disagreements.
The final set held 825 trials, and nearly ninety-eight percent tested treatments. The team recorded phase, size, masking, funding source, and where each trial ran, then compared six five-year periods. Their aim was to see whether trial design, sponsorship, and geography kept pace with recent treatment advances, such as immune drugs moving into first-line care.
Catalog record
| CREATOR | Jian Cui, Jianhua Chen, Hongming Zhang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 25 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |