Narrative review of the staging classification controversy in stage N3 small cell lung cancer: from the perspective of overlapping Veterans Administration Lung Study Group and International Association for the Study of Lung Cancer definitions
Xinyu Chen, Qilin Wang, Juncai Ye, Xueping Yang, Jiahao Chen, Guangzeng Zhou, Chuanyu You, Tian Xu, Yan Gui · 2026
Read Narrative review of the staging classification controversy in stage N3 small cell lung cancer: from the perspective of overlapping Veterans Administration Lung Study Group and International Association for the Study of Lung Cancer definitions by Xinyu Chen, Qilin Wang, Juncai Ye, Xueping Yang, Jiahao Chen, Guangzeng Zhou, Chuanyu You, Tian Xu, Yan Gui (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13559235.txt.
Description
Xinyu Chen and eight co-authors review a staging dispute in small cell lung cancer in a 2026 paper. Two staging systems overlap in a confusing way for patients with advanced node spread. One system calls disease limited when it fits a single radiation field. The other calls it limited when no distant spread exists.
Many node-heavy patients count as extensive under the first system and limited under the second. That clash affects treatment choices and trial grouping. The review uses a structured search to gather the clinical evidence around the overlap. It aims to clarify terms and support shared staging language. Consistent labels would help doctors compare studies and pick therapy with more confidence.
Catalog record
| CREATOR | Xinyu Chen, Qilin Wang, Juncai Ye, Xueping Yang, Jiahao Chen, Guangzeng Zhou, Chuanyu You, Tian Xu, Yan Gui |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 48 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |