Global longitudinal strain and left ventricular ejection fraction for early detection of chemotherapy-related cardiac dysfunction in breast cancer: A prospective comparison of doxorubicin-based and paclitaxel– carboplatin regimens

Rizka Faradilla, Teuku Heriansyah, Novita Novita, Haris Munirwan, Maha Fitra · 2026

Read Global longitudinal strain and left ventricular ejection fraction for early detection of chemotherapy-related cardiac dysfunction in breast cancer: A prospective comparison of doxorubicin-based and paclitaxel– carboplatin regimens by Rizka Faradilla, Teuku Heriansyah, Novita Novita, Haris Munirwan, Maha Fitra (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13558890.txt.

Description

Rizka Faradilla and co-authors compare heart harm from two breast cancer drug plans in a 2026 study. One plan rests on doxorubicin, a drug known to strain the heart. The other pairs paclitaxel with carboplatin. The team tracked 106 women, half on each plan, with heart scans before care and four months in.

Two heart scores frame the test. One, ejection fraction, counts how much blood the heart pumps out. It shifts late, once harm is deep. The other, strain, tracks heart wall stretch and shifts early. At start the groups matched on both scores. At four months the doxorubicin group showed a sharp strain drop, while the other group held near flat. Pump scores barely moved in both groups. The authors back strain scans as the early alarm for heart harm in chemo care.

Catalog record

CREATORRizka Faradilla, Teuku Heriansyah, Novita Novita, Haris Munirwan, Maha Fitra
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE28 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13558890

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