Integrated experimental and computational evaluation of atractylenolide III from Tubipora musica for anticancer lead identification
Hamada A. A. Noreldeen · 2026
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Description
Hamada Noreldeen writes a 2026 study on a coral compound as a cancer lead. Liver cancer causes many deaths each year and needs gentler new drugs. A compound called atractylenolide III was taken from the marine coral Tubipora musica and tested on liver cancer cells.
In lab tests, the compound killed cancer cells in a dose-linked way and cut cell survival sharply at higher doses. Computer docking across many cancer-linked proteins pointed to one strong partner on immune cells. Shape modeling then found a related compound with even stronger binding and good drug-like traits. The author frames the work as a guide for later animal and mechanism studies, not proof of a cure.
Catalog record
| CREATOR | Hamada A. A. Noreldeen |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 53 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |