The impact of GeNeurofil™ nutraceutical supplementation on psychometric assessment and biomarkers of neurodegeneration in cognitive impaired patients: a pilot study
Luigia Trabace, Maria Grazia Morgese, Paolo Tucci, Lisa Pia Agosti, Martina Santoro, Carmen Ritrovato, Rossella Gallotto, Maurizio Tolfa, Sara Nardella, Giuseppe Cristiano, Tonia Bocci, Matteo Bevilacqua · 2026
Read The impact of GeNeurofil™ nutraceutical supplementation on psychometric assessment and biomarkers of neurodegeneration in cognitive impaired patients: a pilot study by Luigia Trabace, Maria Grazia Morgese, Paolo Tucci, Lisa Pia Agosti, Martina Santoro, Carmen Ritrovato, Rossella Gallotto, Maurizio Tolfa, Sara Nardella, Giuseppe Cristiano, Tonia Bocci, Matteo Bevilacqua (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13558051.txt.
Description
Luigia Trabace and eleven colleagues ran a pilot trial in 2026 of a nutraceutical blend called GeNeurofil in people with mild cognitive impairment. This early stage of decline raises dementia risk and still lacks approved treatments. Earlier animal work suggested the blend protects neurons against amyloid toxicity. The team therefore tested it in 54 patients with mild to moderate impairment. The trial ran six months with a randomised, double-blind, placebo-controlled design.
Patients kept their usual medicines and took the blend or an identical placebo three times a day. After six months, the treated group improved on global dementia rating, mental state testing, and a depression scale relative to placebo. Blood levels of two damage markers, neurofilament light and phosphorylated tau, also fell. The authors present the results as pilot evidence that justifies a larger, longer trial.
Catalog record
| CREATOR | Luigia Trabace, Maria Grazia Morgese, Paolo Tucci, Lisa Pia Agosti, Martina Santoro, Carmen Ritrovato, Rossella Gallotto, Maurizio Tolfa, Sara Nardella, Giuseppe Cristiano, Tonia Bocci, Matteo Bevilacqua |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |