Pathology‐Driven Diagnosis of Hereditary Leiomyomatosis and Renal Cell Carcinoma: A Clinicopathological and Genetic Analysis of Three Cases
Tomoko Uchiyama, Shunsuke Okazaki, Sayaka Ando, Maiko Takeda, Makito Miyake, Akihiko Yoshizawa · 2026
Read Pathology‐Driven Diagnosis of Hereditary Leiomyomatosis and Renal Cell Carcinoma: A Clinicopathological and Genetic Analysis of Three Cases by Tomoko Uchiyama, Shunsuke Okazaki, Sayaka Ando, Maiko Takeda, Makito Miyake, Akihiko Yoshizawa (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13557843.txt.
Description
Tomoko Uchiyama and co-authors show how careful pathology work can uncover a hereditary cancer syndrome, in a 2026 paper. The syndrome brings skin and womb growths plus an aggressive kidney cancer from a faulty gene. Only a few hundred families are known worldwide, and the true count is unclear.
Three cases came to light through close tissue study. Two patients had advanced kidney cancer with varied shapes under the microscope. A third had many painful skin growths and no kidney tumor. Gene tests confirmed the syndrome in all three, each with a distinct mutation. The authors stress joint review across clinic, imaging, pathology, and genetics so families are found and watched in time.
Catalog record
| CREATOR | Tomoko Uchiyama, Shunsuke Okazaki, Sayaka Ando, Maiko Takeda, Makito Miyake, Akihiko Yoshizawa |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 12 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |