Codon bias variation in Staphylococcus aureus

Kathleen O’Connor, Benjamin D. Mallinger, Nicholas A. Bedard, Robin Patel, Jordy Evan Sulaiman, Jordy Evan Sulaiman, Jordy Evan Sulaiman, Jordy Evan Sulaiman · 2026

Read Codon bias variation in Staphylococcus aureus by Kathleen O’Connor, Benjamin D. Mallinger, Nicholas A. Bedard, Robin Patel, Jordy Evan Sulaiman, Jordy Evan Sulaiman, Jordy Evan Sulaiman, Jordy Evan Sulaiman (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13557361.txt.

Description

Kathleen O'Connor, Benjamin Mallinger, Nicholas Bedard, and Robin Patel study codon bias variation in Staphylococcus aureus, in a research paper from 2026. The bacterium causes many diseases in community and hospital settings. Most evolution work tracks coding changes, while silent changes in codon choice get less study, so their patterns and effect on protein output were unclear.

Codon use in more than two thousand genes from a reference strain was compared across all closed public genomes. Genomes were sorted by disease state, source lab, and collection site. A standard index scored bias at gene and genome level. Ribosome-linked genes scored highest with tight spread. Scores also tracked measured protein levels in lab data.

Catalog record

CREATORKathleen O’Connor, Benjamin D. Mallinger, Nicholas A. Bedard, Robin Patel, Jordy Evan Sulaiman, Jordy Evan Sulaiman, Jordy Evan Sulaiman, Jordy Evan Sulaiman
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE89 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13557361

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