821. Association of Alcohol-Related Genetic Polymorphisms with Problematic alcohol use and Suicidal Ideation
Y Nago-Iwashita, T Kanata, M Oba, K Ikeda, D Nishizawa · 2026
Read 821. Association of Alcohol-Related Genetic Polymorphisms with Problematic alcohol use and Suicidal Ideation by Y Nago-Iwashita, T Kanata, M Oba, K Ikeda, D Nishizawa (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13556408.txt.
Description
Nago-Iwashita and co-authors ask whether the genes that govern how the body handles alcohol change the link between problem drinking and suicidal thoughts. Two variants in alcohol-processing enzymes are famous in East Asian populations for shaping drinking habits, and both have been tied to mood and suicide risk. Their 2026 Tokyo survey genotypes 699 adults from cheek swabs and sorts them into five combined genotype groups.
Problem drinking, present in about twenty-seven percent, tracked strongly with genotype. Across everyone, its link to suicidal ideation was not significant. Inside one genotype group, though, those with fast alcohol clearance on both enzymes, the link was clear and significant, while a neighboring group showed none. The authors read the split as effect modification: the same drinking pattern may carry different mental health weight depending on the genes that process the alcohol.
Catalog record
| CREATOR | Y Nago-Iwashita, T Kanata, M Oba, K Ikeda, D Nishizawa |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 4 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |