47. Early improvement predicts subsequent antidepressant response to intravenous ketamine
O Syed, F Alam, P Giacobbe · 2026
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Description
Syed, Alam, and Giacobbe ask whether early gains predict who benefits from ketamine treatment for stubborn depression, in a 2026 conference abstract. A third of depression patients fail standard treatments. Infused ketamine can act fast, but courses are costly and demanding.
The team reviewed 77 clinic patients who received eight ketamine doses over four to five weeks. Mood scores were logged before each dose. The question was whether the score after the second dose foreshadowed the final outcome. Full response meant at least halving the score. The analysis aims to guide talks about continuing or stopping treatment. Early signals could spare nonresponders a long, hard course.
Catalog record
| CREATOR | O Syed, F Alam, P Giacobbe |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 4 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |