Association of glycolipid metabolism 6 factors index with cardiovascular and metabolic diseases, and its predictive value in disease progression

Jiahui Qi, Lingyu Liu, Yijin Pan, Yihan Wang, Xitong Xu, Haipeng Wang, Yiyan Li, Qian Liu, Songwen Liu, Chen Li, Yuqing He · 2026

Read Association of glycolipid metabolism 6 factors index with cardiovascular and metabolic diseases, and its predictive value in disease progression by Jiahui Qi, Lingyu Liu, Yijin Pan, Yihan Wang, Xitong Xu, Haipeng Wang, Yiyan Li, Qian Liu, Songwen Liu, Chen Li, Yuqing He (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13556023.txt.

Description

Jiahui Qi and ten colleagues tested in 2026 whether simple combined blood indices can flag people at high risk of heart and metabolic disease. They built two scores from routine glucose and lipid measures. One score uses six factors and the other uses seven. Both were checked against disease records in a large United States survey and a Chinese ageing cohort. Machine learning models measured how well each score predicted illness.

Both scores rose alongside risk across nine disease groups and fourteen specific conditions, plus death, with thyroid overactivity the lone exception. The six-factor version predicted about as well as the seven-factor one for most diseases, especially heart and metabolic conditions. Follow-up data linked higher six-factor scores, and scores that stayed high over time, to new cardiovascular disease and diabetes. A short panel of routine tests may thus serve long-term risk monitoring.

Catalog record

CREATORJiahui Qi, Lingyu Liu, Yijin Pan, Yihan Wang, Xitong Xu, Haipeng Wang, Yiyan Li, Qian Liu, Songwen Liu, Chen Li, Yuqing He
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE87161
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13556023

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