Decoding protein signatures and protein interactions in oral potentially malignant disorders: a systematic review and network analysis

Bounika Esvanth Rao, Anju M. Nair, Preethi Ramesh, Vijayalakshmi Ramshankar, S. Gopinath, P. A. Abhinand, Artnora Ndkoraj, Marta Mazur, Saman Warnakulasuriya, Divyambika Catakapatri Venugopal · 2026

Read Decoding protein signatures and protein interactions in oral potentially malignant disorders: a systematic review and network analysis by Bounika Esvanth Rao, Anju M. Nair, Preethi Ramesh, Vijayalakshmi Ramshankar, S. Gopinath, P. A. Abhinand, Artnora Ndkoraj, Marta Mazur, Saman Warnakulasuriya, Divyambika Catakapatri Venugopal (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13555922.txt.

Description

Bounika Esvanth Rao leads a ten-author team reviewing protein clues in mouth conditions that can precede cancer in a 2026 analysis. Such disorders include white patches, stiffening of the mouth lining, and lichen-like changes. From nearly thirteen thousand papers, fifteen studies passed the quality screen. The team counted repeated proteins, built interaction networks, and traced hub proteins to their pathways.

Most included work covered the stiffening disorder, with fewer studies on the other lesions. Four studies earned top quality marks. Shared and lesion-specific proteins emerged from the vote counting. Hub proteins, the most connected in each network, pointed to pathways worth drug targeting. The authors present the synthesis as a guide for biomarker hunts in these hard-to-read conditions.

Catalog record

CREATORBounika Esvanth Rao, Anju M. Nair, Preethi Ramesh, Vijayalakshmi Ramshankar, S. Gopinath, P. A. Abhinand, Artnora Ndkoraj, Marta Mazur, Saman Warnakulasuriya, Divyambika Catakapatri Venugopal
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE87572
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13555922

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