Sex, Timing, and Outcomes of Curative-Intent Immunotherapy
Anne-Murielle Hollinger, Camille L. Gerard, Victoria J. Andreas, Zayne M. Roa Diaz, Silke Gillessen, Olivier Michielin, Miklos Pless, Solange Peters, Charlotte Micheloud, Stefanie Hayoz, Berna C. Özdemir, Sabine Schmid · 2026
Read Sex, Timing, and Outcomes of Curative-Intent Immunotherapy by Anne-Murielle Hollinger, Camille L. Gerard, Victoria J. Andreas, Zayne M. Roa Diaz, Silke Gillessen, Olivier Michielin, Miklos Pless, Solange Peters, Charlotte Micheloud, Stefanie Hayoz, Berna C. Özdemir, Sabine Schmid (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13555367.txt.
Description
Hollinger and co-authors pooled trial evidence on whether sex and timing change the payoff of immune therapy given to cure solid tumors, published in 2026. Immune checkpoint drugs are moving from last-resort use into curative plans, before or after surgery. Whether they work equally in men and women is underexplored. Timing is shifting too, toward treatment before surgery. The team searched the main medical databases and trial registries systematically.
Their meta-analysis weighs outcomes by both factors together. A sex gap, if real, would argue for tailored dosing or scheduling. A timing effect could settle a live practice debate. Curative settings raise the stakes: these patients may live decades with the consequences. The synthesis assembles the scattered randomized evidence into one answer. It is meant to guide oncologists choosing regimens now.
Catalog record
| CREATOR | Anne-Murielle Hollinger, Camille L. Gerard, Victoria J. Andreas, Zayne M. Roa Diaz, Silke Gillessen, Olivier Michielin, Miklos Pless, Solange Peters, Charlotte Micheloud, Stefanie Hayoz, Berna C. Özdemir, Sabine Schmid |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |