Longitudinal changes in left atrial function during chronic ibrutinib therapy: a prospective observational study
Matea Kolacevic Zeljkovic, Sandra Basic-Kinda, Dubravka Čaržavec, Marijo Vodanovic, Inga Mandac Smoljanovic, Ozren Jaksic, Matea Novak, Slobodanka Ostojic-Kolonic, Dino Dujmovic, Vlatko Pejsa, Igor Aurer, Nikola Bulj · 2026
Read Longitudinal changes in left atrial function during chronic ibrutinib therapy: a prospective observational study by Matea Kolacevic Zeljkovic, Sandra Basic-Kinda, Dubravka Čaržavec, Marijo Vodanovic, Inga Mandac Smoljanovic, Ozren Jaksic, Matea Novak, Slobodanka Ostojic-Kolonic, Dino Dujmovic, Vlatko Pejsa, Igor Aurer, Nikola Bulj (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13553814.txt.
Description
A cancer drug that can strain the heart is tracked over time in a 2026 study by Matea Kolacevic Zeljkovic and co-authors. The drug, ibrutinib, treats B-cell cancers but is linked to rhythm problems and high blood pressure, and little is known about how the heart's left atrium changes during long use.
Forty patients starting the drug had heart checks, rhythm monitoring, and ultrasound scans at the start and at set points up to about three years. The left atrium grew slowly over time, with its volume index rising at each check. Measures of how well the atrium stretches began to worsen from six months on. The study maps a slow change that doctors may want to watch.
Catalog record
| CREATOR | Matea Kolacevic Zeljkovic, Sandra Basic-Kinda, Dubravka Čaržavec, Marijo Vodanovic, Inga Mandac Smoljanovic, Ozren Jaksic, Matea Novak, Slobodanka Ostojic-Kolonic, Dino Dujmovic, Vlatko Pejsa, Igor Aurer, Nikola Bulj |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |