Association between serum tumor necrosis factor-alpha levels and rheumatoid arthritis-associated interstitial lung disease: a cross-sectional study
Xiaoli Li, Lina Leng, Yaorong Han, Jinfeng Zhang, Xinfang Shang, Shusen Zhang, Dengxiang Liu, Yuhua Qiao · 2026
Read Association between serum tumor necrosis factor-alpha levels and rheumatoid arthritis-associated interstitial lung disease: a cross-sectional study by Xiaoli Li, Lina Leng, Yaorong Han, Jinfeng Zhang, Xinfang Shang, Shusen Zhang, Dengxiang Liu, Yuhua Qiao (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13553761.txt.
Description
Lung scarring is among the gravest complications of rheumatoid arthritis, and a key inflammation protein may be involved. Xiaoli Li and co-authors measured that protein, TNF-alpha, in the blood of arthritis patients at one Chinese hospital. Records covered one thousand one hundred ninety-one patients, with seven hundred ninety in the final analysis. About nineteen percent had lung disease on chest scans. Men were affected far more often than women.
After adjustments, higher protein levels linked to lung disease in women but the pattern differed by sex. The highest third of levels nearly doubled the odds for women. The authors suggest blood levels could help flag women at risk. A snapshot study cannot prove cause, and they frame the link as a lead for follow-up.
Catalog record
| CREATOR | Xiaoli Li, Lina Leng, Yaorong Han, Jinfeng Zhang, Xinfang Shang, Shusen Zhang, Dengxiang Liu, Yuhua Qiao |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 46 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |