Case Report: Sinonasal plasmablastic lymphoma in a human immunodeficiency virus-negative elderly woman diagnosed by immunohistochemistry
Savitri M. Nerune, Sayandeep K. Das, Shivshankar Ajur, Ishan Garg · 2026
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Description
A 75-year-old woman arrived with a blocked left nostril, watery discharge, and one nosebleed, and scans showed a destructive mass filling her left nasal cavity and sinuses. Savitri Nerune and co-authors report the case in 2026. She had no HIV infection, no transplant, and no immune suppression, which made the final diagnosis a surprise.
Under the microscope the growth looked like several cancers at once, from undifferentiated carcinoma to melanoma. A wide stain panel settled it: plasmablastic lymphoma, a rare and aggressive B-cell cancer that usually strikes the mouths of immune-weakened patients. The tumour carried plasma cell markers, a kappa light chain pattern, and a growth index near 99 percent. After three rounds of CHOP chemotherapy her breathing eased, though no follow-up scan was available to grade the response.
Catalog record
| CREATOR | Savitri M. Nerune, Sayandeep K. Das, Shivshankar Ajur, Ishan Garg |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 22 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |