Efficacy of conbercept pro re nata (PRN) versus treat-and-extend (T&E) regimens following five initial monthly doses in diabetic macular edema: a 24-month retrospective cohort study
Mengyao Yang, Pengfei Jiang, Yuanqing Liu, Jie Wang, Xiaonan Zhao, Nan Wang, Yuan Tao, Hong Wang · 2026
Read Efficacy of conbercept pro re nata (PRN) versus treat-and-extend (T&E) regimens following five initial monthly doses in diabetic macular edema: a 24-month retrospective cohort study by Mengyao Yang, Pengfei Jiang, Yuanqing Liu, Jie Wang, Xiaonan Zhao, Nan Wang, Yuan Tao, Hong Wang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13553420.txt.
Description
Yang and co-authors compare two dosing styles for an eye drug treating diabetic macular swelling, after five monthly starter shots. One style injects only when disease returns; the other stretches visit gaps while treating each time. Their 2026 study reviews 119 patients over twenty four months, tracking vision, retinal thickness, and small vessel measures.
Both groups improved in vision and anatomy from six months on, and gains held to two years. No outcome differed clearly between the styles. The stretch style, though, needed fewer injections, about eleven against fourteen, and far fewer visits, about fourteen against twenty five. The authors conclude the drug is safe and effective, and the stretch style lightens the treatment burden.
Catalog record
| CREATOR | Mengyao Yang, Pengfei Jiang, Yuanqing Liu, Jie Wang, Xiaonan Zhao, Nan Wang, Yuan Tao, Hong Wang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 58 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |