Efficacy and safety of edaravone dexborneol for acute ischemic stroke: a meta-analysis
Xinxiu Shi, Yukai Wang, Renjie Wang, Xiaohua Shi, Lei Xu · 2026
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Description
Xinxiu Shi and co-authors pooled trial results on a drug pair for acute stroke in a 2026 analysis. The pair joins edaravone with dexborneol, and it is used for strokes caused by a blocked brain artery. Single trials were small, so the team gathered randomized trials and cohort studies from five databases and judged their quality with a standard bias tool.
Fifty-four studies entered the pool. Patients on the drug pair improved more on a standard stroke severity scale over the first two weeks than control patients did. The gain held across mild, moderate, and severe stroke groups, and grew with severity. The team also tracked recovery at ninety days and side effects during treatment and the three months after, to weigh benefit against harm.
Catalog record
| CREATOR | Xinxiu Shi, Yukai Wang, Renjie Wang, Xiaohua Shi, Lei Xu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 52 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |