Rescue Tirofiban for Early Neurological Deterioration After Tenecteplase in Capsular Warning Syndrome

Claudia Cuccurullo, Antonio De Mase, Paolo Candelaresi, Vincenzo Andreone · 2026

Read Rescue Tirofiban for Early Neurological Deterioration After Tenecteplase in Capsular Warning Syndrome by Claudia Cuccurullo, Antonio De Mase, Paolo Candelaresi, Vincenzo Andreone (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13553178.txt.

Description

Claudia Cuccurullo and co-authors describe a rescue drug choice for a stroke patient who worsened after clot-busting treatment, in a 2026 letter. The forty-seven-year-old man had capsular warning syndrome, a pattern of repeated small deficits that often ends in a capsular stroke. He arrived with a fluctuating weak left side an hour after onset and scored eight on the standard stroke scale.

Scans showed no blocked large vessel, and tenecteplase went in within fifteen minutes of arrival. The letter follows his early decline and the team's turn to tirofiban, a fast platelet blocker. Cases like this test how doctors should act when the first treatment fails in a syndrome known for sudden turns.

Catalog record

CREATORClaudia Cuccurullo, Antonio De Mase, Paolo Candelaresi, Vincenzo Andreone
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE6 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13553178

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