The CPKs‐CBP60b positive feedback loop regulates immunity in Arabidopsis
Lu‐Shen Li, Lin Ma, Yun‐Xia Chen, Sha Li · 2026
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Description
Lu-Shen Li and co-authors uncover a self-reinforcing loop in plant immunity in a 2026 study. When pathogens attack a plant, a switch protein called CBP60b turns on defense genes. The team found that a family of calcium-driven enzymes grabs this switch and adds a phosphate tag at one specific spot, which makes the switch work harder.
A version of the switch that cannot take the tag left plants weakly defended, while a version that mimics the tag made them resist infection better. The loop closes because the switch itself turns on the genes for those enzymes, and sick plants make more of both partners. The finding explains how plants amplify a faint danger signal into a full defense. Breeders and biotechnologists may use such loops to build crops that fight disease with less chemical help.
Catalog record
| CREATOR | Lu‐Shen Li, Lin Ma, Yun‐Xia Chen, Sha Li |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 42 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |