Dissecting the cell biology of the ISR in cognitive disorders at the single-cell resolution
Bong-Kiun Kaang · 2026
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Description
Bong-Kiun Kaang wrote a 2026 comment on how brain cells handle stress and how that links to thinking problems. Cells use a shared stress reply, called the ISR, to tune protein making when conditions turn hard. In the brain, that reply helps form long-term memory, but when it stays on too long it can harm nerve cells.
Kaang draws on a new study that tracked the stress reply one cell at a time. The reply differed a lot by cell type, which may explain why some cells cope and others fail. That split opens a fresh way to think about memory loss and to aim future care at the right cells.
Catalog record
| CREATOR | Bong-Kiun Kaang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 13 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |