Natural products targeting hepatitis B virus X protein and HBx-associated pathways in HBV-related hepatocellular carcinoma: mechanisms and therapeutic potential
Thu Ngoc Anh Nguyen, Piyanoot Thongsri, Yongyut Pewkliang, Mullika Traidej Chomnawang, Krit Thirapanmethee, Khanit Sa-ngiamsuntorn · 2026
Read Natural products targeting hepatitis B virus X protein and HBx-associated pathways in HBV-related hepatocellular carcinoma: mechanisms and therapeutic potential by Thu Ngoc Anh Nguyen, Piyanoot Thongsri, Yongyut Pewkliang, Mullika Traidej Chomnawang, Krit Thirapanmethee, Khanit Sa-ngiamsuntorn (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13552325.txt.
Description
Thu Ngoc Anh Nguyen and co-authors review in 2026 natural products that target a hepatitis B virus protein driving liver cancer. The viral protein, called HBx, helps the virus persist and pushes liver cells toward cancer by disturbing gene control, repair, and cell death. Curative options for advanced cancer remain limited, so multi-target natural compounds draw interest as candidates.
The review weighs a decade of lab, animal, and clinical evidence. Some products cut virus replication by lowering the protein or speeding its breakdown. Others act on cancer pathways the protein drives, including spread and drug resistance. The authors map both direct and indirect effects.
Catalog record
| CREATOR | Thu Ngoc Anh Nguyen, Piyanoot Thongsri, Yongyut Pewkliang, Mullika Traidej Chomnawang, Krit Thirapanmethee, Khanit Sa-ngiamsuntorn |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 81 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |