Effects of personalized transcranial magnetic stimulation on social cognitive network functional connectivity in schizophrenia spectrum disorders: A double-blind, randomized, sham-controlled target engagement trial

Lindsay D. Oliver, Daniel M. Blumberger, Zhi-De Deng, Colin Hawco, Erin W. Dickie, Julia Gallucci, Jerrold Jeyachandra, Salim Mansour, Stephanie M. Hare, James M. Gold, George Foussias, Miklos Argyelan, Zafiris J. Daskalakis, Robert W. Buchanan, Anil K. Malhotra, Aristotle N. Voineskos · 2026

Read Effects of personalized transcranial magnetic stimulation on social cognitive network functional connectivity in schizophrenia spectrum disorders: A double-blind, randomized, sham-controlled target engagement trial by Lindsay D. Oliver, Daniel M. Blumberger, Zhi-De Deng, Colin Hawco, Erin W. Dickie, Julia Gallucci, Jerrold Jeyachandra, Salim Mansour, Stephanie M. Hare, James M. Gold, George Foussias, Miklos Argyelan, Zafiris J. Daskalakis, Robert W. Buchanan, Anil K. Malhotra, Aristotle N. Voineskos (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13551969.txt.

Description

Oliver and colleagues ran a brain stimulation trial in 2026 for social thinking problems in schizophrenia spectrum disorders. These disorders often impair social cognition, meaning skills such as reading others' minds, with few treatments available. The team targeted the dorsomedial prefrontal cortex, a brain area for social processing, with magnetic stimulation. Forty-six adults finished two weeks of one of three options: standard rapid stimulation, a burst pattern, or sham treatment.

The burst pattern, called iTBS, raised connectivity inside the mentalizing network, the brain system for thinking about minds, far more than sham. Pain ratings were higher with the burst pattern, but dropout and side effect rates matched the other groups. The authors say the burst method hit its brain target and merits a larger clinical trial.

Catalog record

CREATORLindsay D. Oliver, Daniel M. Blumberger, Zhi-De Deng, Colin Hawco, Erin W. Dickie, Julia Gallucci, Jerrold Jeyachandra, Salim Mansour, Stephanie M. Hare, James M. Gold, George Foussias, Miklos Argyelan, Zafiris J. Daskalakis, Robert W. Buchanan, Anil K. Malhotra, Aristotle N. Voineskos
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE33 KB
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13551969

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