Impact of a comprehensive healthy lifestyle score on a broad spectrum of cardiometabolic and related diseases and its incremental value for risk prediction based on the UK biobank database
Xinyue Chen, Sen Han, Yating Chen, Sheng Yuan, Jining He, Zixiang Ye, Yanjun Song, Kefei Dou · 2026
Read Impact of a comprehensive healthy lifestyle score on a broad spectrum of cardiometabolic and related diseases and its incremental value for risk prediction based on the UK biobank database by Xinyue Chen, Sen Han, Yating Chen, Sheng Yuan, Jining He, Zixiang Ye, Yanjun Song, Kefei Dou (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13551960.txt.
Description
Xinyue Chen, with seven colleagues, published a 2026 study of lifestyle and disease in the UK Biobank. The cohort held 148,155 adults free of the studied diseases at the start. Five habits formed a healthy lifestyle score. They were not smoking, modest drinking, regular activity, a healthy diet, and healthy sleep. Outcomes covered eleven heart, metabolic, and related diseases.
Most single habits tied to lower disease risk. The combined score showed a clear step pattern. The healthiest group had much lower risk than the least healthy group. The strongest link was for pulmonary hypertension, a lung vessel disease. Healthy sleep carried the largest weight in the score. Adding lifestyle to standard risk models improved prediction a bit.
Catalog record
| CREATOR | Xinyue Chen, Sen Han, Yating Chen, Sheng Yuan, Jining He, Zixiang Ye, Yanjun Song, Kefei Dou |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 48427 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |