Icariin-loaded liposomal nanoparticles alleviate streptozotocin-induced diabetic hepatopathy associated with modulation of ferroptosis-related and inflammatory signaling

Badriah A. Hifni, Shaza A. Alyamani, Nasser S. Alqahtani, Ayat B. Al-Ghafari, Huda A. Al Doghaither, Ekramy M. Elmorsy, Manal S. Fawzy, Gehad E. Elshopakey · 2026

Read Icariin-loaded liposomal nanoparticles alleviate streptozotocin-induced diabetic hepatopathy associated with modulation of ferroptosis-related and inflammatory signaling by Badriah A. Hifni, Shaza A. Alyamani, Nasser S. Alqahtani, Ayat B. Al-Ghafari, Huda A. Al Doghaither, Ekramy M. Elmorsy, Manal S. Fawzy, Gehad E. Elshopakey (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13551826.txt.

Description

Badriah Hifni and co-authors test in 2026 whether a plant compound, packed into tiny fat bubbles, can ease liver harm in diabetic rats. Diabetes can damage the liver through poor fuel handling, cell stress, swelling, and a form of cell death tied to iron. The compound guards the liver in past work, but the body absorbs it poorly.

Ninety rats were split into six groups of fifteen. Some stayed healthy, some were made diabetic with a drug, and the diabetic groups got the compound free or in bubbles. The bubble form is meant to carry more of it to the liver. The team tracked liver health and the signals tied to swelling and the iron linked death path. A better delivery form could turn a weak plant compound into a useful guard.

Catalog record

CREATORBadriah A. Hifni, Shaza A. Alyamani, Nasser S. Alqahtani, Ayat B. Al-Ghafari, Huda A. Al Doghaither, Ekramy M. Elmorsy, Manal S. Fawzy, Gehad E. Elshopakey
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE83 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13551826

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