LINAC-based stereotactic radiosurgery targeting the hippocampus in mesial temporal lobe epilepsy: a single-center case series
Víctor Alberto García-García, Marco Vinicio Ramírez-Sánchez, Roberto Carlos García-Romero, Isaac Jasso-García, David Garcia-Martinez, Aldo Tavares-Ortega, Andrea Miriam Gonzalez-Gonzalez, Rubí Carolina Estrada-Hernández, María Fernanda Sánchez-Miranda, Guadalupe Castillo-Cardiel, Gabino Cervantes-Gu · 2026
Read LINAC-based stereotactic radiosurgery targeting the hippocampus in mesial temporal lobe epilepsy: a single-center case series by Víctor Alberto García-García, Marco Vinicio Ramírez-Sánchez, Roberto Carlos García-Romero, Isaac Jasso-García, David Garcia-Martinez, Aldo Tavares-Ortega, Andrea Miriam Gonzalez-Gonzalez, Rubí Carolina Estrada-Hernández, María Fernanda Sánchez-Miranda, Guadalupe Castillo-Cardiel, Gabino Cervantes-Gu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13551764.txt.
Description
Víctor García-García and co-authors published this case series in 2026. It tries focused radiation as an alternative to brain surgery for stubborn temporal lobe epilepsy. Removing the seizure source works, but risks memory and language, and many patients refuse or cannot risk it. Seven patients with drug-resistant one-sided disease got a single high radiation dose aimed at the hippocampus, delivered by a linear accelerator. Seizure counts were tracked for twenty-four months.
Median monthly seizures fell from twelve to three and a half, a cut of about three quarters. No patient became fully seizure free. Still, about seventy-one percent kept at least a halving of seizures across the follow-up. The team frames radiation as a gentler fallback for patients shut out of surgery. The series is small and exploratory, meant to size up a fuller trial.
Catalog record
| CREATOR | Víctor Alberto García-García, Marco Vinicio Ramírez-Sánchez, Roberto Carlos García-Romero, Isaac Jasso-García, David Garcia-Martinez, Aldo Tavares-Ortega, Andrea Miriam Gonzalez-Gonzalez, Rubí Carolina Estrada-Hernández, María Fernanda Sánchez-Miranda, Guadalupe Castillo-Cardiel, Gabino Cervantes-Gu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |