Organocatalytic stereoselective C–H diazenylation of active methylenes with arenediazonium salts
Aqsa, Alaud Din, Mehtab Ahmad, Hammad Khan, Muhammad Israr, Syed Osama, Qudrat Ullah, Sumbal Saba, Zi-Sheng Chen, Syed Adnan Ali Shah, Shaukat Ali · 2026
Read Organocatalytic stereoselective C–H diazenylation of active methylenes with arenediazonium salts by Aqsa, Alaud Din, Mehtab Ahmad, Hammad Khan, Muhammad Israr, Syed Osama, Qudrat Ullah, Sumbal Saba, Zi-Sheng Chen, Syed Adnan Ali Shah, Shaukat Ali (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13551556.txt.
Description
Aqsa and ten co-authors attached nitrogen groups to carbon skeletons cleanly in this study from twenty twenty-six. Hydrazones are prized building blocks, classically made by a reaction that throws away a fragment. The team used an organic catalyst and diazonium salts under plain room conditions. No additives were needed.
Yields reached up to ninety-nine percent across a wide range of starting materials. Selectivity for the right site and the right bond was excellent. One fluorinated partner gave only the Z-shaped product, a first for this catalysis style. Internal hydrogen bonding explains both the stability and that shape preference. Green chemistry scores for the process looked strong. The authors also demonstrated valuable target molecules.
Catalog record
| CREATOR | Aqsa, Alaud Din, Mehtab Ahmad, Hammad Khan, Muhammad Israr, Syed Osama, Qudrat Ullah, Sumbal Saba, Zi-Sheng Chen, Syed Adnan Ali Shah, Shaukat Ali |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 20 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |