Methylchloroisothiazolinone and Methylisothiazolinone 10 Years After Regulation: A Case Story of Liquid Soaps and Shampoos
Mathias Krogh Pedersen, Jakob Ferløv Baselius Schwensen, Jose Hernán Alfonso, Christel Søgaard Kirkeby, Stine Müller, Steen Mollerup, Gianluca Selvestrel, Christina Rudén, Martin F Wilks, Jeanne Duus Johansen · 2026
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Description
Mathias Krogh Pedersen, leading nine colleagues, published a 2026 study checking whether two preservative allergens still appear in Danish cosmetics ten years after European regulation. Methylchloroisothiazolinone and methylisothiazolinone, known as MCI and MI, prevent spoilage in water-based products but cause contact allergy. Using a Danish product database, the team found 257 products listing them, then chemically analyzed thirty shampoos and liquid soaps.
Most identified products were shampoos and conditioners. Two of twenty-five labeled products exceeded the 15 parts per million limit for rinse-off goods, and four missed the required ratio between the two preservatives. Since allergy remains common despite rare use, the authors suggest the legal limit may still be too high to protect users.
Catalog record
| CREATOR | Mathias Krogh Pedersen, Jakob Ferløv Baselius Schwensen, Jose Hernán Alfonso, Christel Søgaard Kirkeby, Stine Müller, Steen Mollerup, Gianluca Selvestrel, Christina Rudén, Martin F Wilks, Jeanne Duus Johansen |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 29201 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |