Diagnostic impact and reproducibility of p53 immunohistochemistry in Barrett's oesophagus: results of the Dutch Esophageal Pathology Panel (DEPP)
Ylva A. Weeda, Sarah M. Issa, Hans Halfwerk, Michel Botros, Onno J. de Boer, Lodewijk A. Brosens, Michail Doukas, Gursah Kats‐Ugurlu, Fiebo ten Kate, Jaap van der Laan, Ineke van Lijnschoten, Ariadne H. A. G. Ooms, Lindsey Oudijk, Rachel S. van der Post, Mihaela G. Raicu, Bert Timmer, Myrtle J. van der Wel, Sybren L. Meijer · 2026
Read Diagnostic impact and reproducibility of p53 immunohistochemistry in Barrett's oesophagus: results of the Dutch Esophageal Pathology Panel (DEPP) by Ylva A. Weeda, Sarah M. Issa, Hans Halfwerk, Michel Botros, Onno J. de Boer, Lodewijk A. Brosens, Michail Doukas, Gursah Kats‐Ugurlu, Fiebo ten Kate, Jaap van der Laan, Ineke van Lijnschoten, Ariadne H. A. G. Ooms, Lindsey Oudijk, Rachel S. van der Post, Mihaela G. Raicu, Bert Timmer, Myrtle J. van der Wel, Sybren L. Meijer (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13551266.txt.
Description
Ylva A. Weeda, with a large panel of co-authors, published a 2026 Dutch study of p53 staining in Barrett's oesophagus. The stain helps flag abnormal cells in the food pipe. Most proof came from hand-picked case sets. Here an expert panel re-read 1,146 referred cases. They compared hospital calls and tested accord among panel members.
Accord between hospitals and the panel was fair to strong. Yet about a quarter of stain calls changed on re-reading. Panel members also agreed well with each other. Abnormal stains moved some normal cases toward doubt or early change. They also settled many doubtful cases. The team calls the stain reliable and able to change real diagnoses.
Catalog record
| CREATOR | Ylva A. Weeda, Sarah M. Issa, Hans Halfwerk, Michel Botros, Onno J. de Boer, Lodewijk A. Brosens, Michail Doukas, Gursah Kats‐Ugurlu, Fiebo ten Kate, Jaap van der Laan, Ineke van Lijnschoten, Ariadne H. A. G. Ooms, Lindsey Oudijk, Rachel S. van der Post, Mihaela G. Raicu, Bert Timmer, Myrtle J. van der Wel, Sybren L. Meijer |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 27652 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |