Self-Assembled Cationic Phthalocyanine Nanophotosensitizer Drives Hypoxia-Tolerant Photodynamic Immunotherapy for HCC
Fang-Cheng Jiang, Yue Qin, Li Gao, Su-Ning Li, Wei Su, Xue-Mei Sun, Xin Chen, Ying Wang, Zhen-Bo Feng, Ze-Feng Lai · 2026
Read Self-Assembled Cationic Phthalocyanine Nanophotosensitizer Drives Hypoxia-Tolerant Photodynamic Immunotherapy for HCC by Fang-Cheng Jiang, Yue Qin, Li Gao, Su-Ning Li, Wei Su, Xue-Mei Sun, Xin Chen, Ying Wang, Zhen-Bo Feng, Ze-Feng Lai (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13550842.txt.
Description
Fang-Cheng Jiang and co-authors published this cancer study in 2026 on liver tumors. Light-based therapy, called photodynamic therapy, kills tumors with reactive oxygen made on the spot. Old drugs for it dissolve poorly and need lots of oxygen, which deep tumors lack. The team built tiny particles from a changed silicon dye that stack up on their own and dissolve well in water.
The particles work through a path that sips oxygen rather than gulping it. Treated tumor cells died in a way that alerts the immune system, spilling warning signals. Those signals ripened the sentry cells that teach killer T cells, and more killers entered the tumors. In mice, the therapy shrank liver tumors and woke body-wide defense. The authors offer the particles as a joint light-and-immune weapon for low-oxygen tumors.
Catalog record
| CREATOR | Fang-Cheng Jiang, Yue Qin, Li Gao, Su-Ning Li, Wei Su, Xue-Mei Sun, Xin Chen, Ying Wang, Zhen-Bo Feng, Ze-Feng Lai |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 71 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |