Electrospun poly(lactic acid) biopolymer fibers functionalized with Y-sperm-specific scFv enable immunoaffinity-driven bovine sperm sexing
Phanuwit Paitoon, Marninphan Thongkham, Kittisak Jantanasakulwong, Aphisit Saenjaiban, Apinya Sartsook, Surat Hongsibsong, Nuttapol Tanadchangsaeng, Pornchai Rachtanapun, Korawan Sringarm · 2026
Read Electrospun poly(lactic acid) biopolymer fibers functionalized with Y-sperm-specific scFv enable immunoaffinity-driven bovine sperm sexing by Phanuwit Paitoon, Marninphan Thongkham, Kittisak Jantanasakulwong, Aphisit Saenjaiban, Apinya Sartsook, Surat Hongsibsong, Nuttapol Tanadchangsaeng, Pornchai Rachtanapun, Korawan Sringarm (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13550498.txt.
Description
Phanuwit Paitoon and colleagues spin plastic fibers coated with a Y-chromosome-targeting antibody fragment to sort cattle sperm by sex, in a 2026 proof-of-concept study. Dairy farmers want heifer calves and beef producers want males, and the standard sorting machine is costly. Their mat of electrospun polylactic acid fibers carries an engineered antibody that grabs only Y-bearing sperm, letting the X-bearing fraction flow past.
Trials tuned the fiber recipe, settling on a mat spun from an eight percent solution, and a battery of imaging and chemical tests confirmed the antibody stayed attached after coupling. Packed into a syringe, the mat enriched the flow-through fraction to about seventy-one percent X-sperm and the captured, released fraction to about seventy-six percent Y-sperm. The authors present the biodegradable platform as a cheaper sorting route worth optimizing.
Catalog record
| CREATOR | Phanuwit Paitoon, Marninphan Thongkham, Kittisak Jantanasakulwong, Aphisit Saenjaiban, Apinya Sartsook, Surat Hongsibsong, Nuttapol Tanadchangsaeng, Pornchai Rachtanapun, Korawan Sringarm |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 76196 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |