HMMR+ stromal cells drive human uterine development

Jiahui Qi, Xiaoqiang Sheng, Shiyuan Li, Peipei Jiang, Huiyan Wang, Lingxi Li, Jidong Zhou, Yifan Li, Huidan Zhang, Miaomiao Wang, Yang Zhang, Guangfeng Zhao, Guijun Yan, Bruno Péault, Yali Hu, Haixiang Sun, Lijun Ding · 2026

Read HMMR+ stromal cells drive human uterine development by Jiahui Qi, Xiaoqiang Sheng, Shiyuan Li, Peipei Jiang, Huiyan Wang, Lingxi Li, Jidong Zhou, Yifan Li, Huidan Zhang, Miaomiao Wang, Yang Zhang, Guangfeng Zhao, Guijun Yan, Bruno Péault, Yali Hu, Haixiang Sun, Lijun Ding (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13550414.txt.

Description

Qi leads a large team identifying a stromal cell type that drives human uterus development in a 2026 paper. Early uterine growth shapes later reproductive health, yet its cell origins were poorly known. Adult tissue had been mapped far more than developing tissue.

Single-cell and spatial data from fetal and adolescent uteri revealed stromal cells marked by a surface receptor. These cells divided fast and could become stromal or muscle-like cells in dishes. Transplanted into mice, they formed tissue with both marker types. Signals from them guided the lining cells to mature. The cells were scarce in thin endometrium cases. The authors call them a key progenitor population for the organ.

Catalog record

CREATORJiahui Qi, Xiaoqiang Sheng, Shiyuan Li, Peipei Jiang, Huiyan Wang, Lingxi Li, Jidong Zhou, Yifan Li, Huidan Zhang, Miaomiao Wang, Yang Zhang, Guangfeng Zhao, Guijun Yan, Bruno Péault, Yali Hu, Haixiang Sun, Lijun Ding
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE75 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13550414

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