Severe corneal melting with necrotic sloughing in Acanthamoeba keratitis mimicking corneal endotheliitis
Yukihiko Nakajima, Hiroko Takano, Yuka Kondo, Ryo Taguchi, Machiko Shimmura-Tomita, Toshikatsu Kaburaki, Suguru Nakagawa · 2026
Read Severe corneal melting with necrotic sloughing in Acanthamoeba keratitis mimicking corneal endotheliitis by Yukihiko Nakajima, Hiroko Takano, Yuka Kondo, Ryo Taguchi, Machiko Shimmura-Tomita, Toshikatsu Kaburaki, Suguru Nakagawa (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13550268.txt.
Description
Yukihiko Nakajima and colleagues describe a corneal infection that hid behind the mask of a viral inflammation for months, in a 2026 case report. A forty-eight-year-old contact lens wearer arrived with a painful red eye, a cloudy swollen cornea, and inflammation inside the eye. Yet she showed none of the classic signs of Acanthamoeba keratitis, a parasitic infection of lens users. Virus tests on eye fluid were negative, so steroids were given for presumed viral endotheliitis.
Scrapings later found no microbes by microscope, culture, or genetic testing, and the cornea kept necrotizing despite revised anti-infective treatment. At thirty-four weeks, the dead corneal tissue sloughed off on its own. Under the microscope, that tissue held the double-walled cysts of Acanthamoeba, finally proving the diagnosis. The authors warn that this infection can mimic inner-eye inflammation and defeat standard sampling.
Catalog record
| CREATOR | Yukihiko Nakajima, Hiroko Takano, Yuka Kondo, Ryo Taguchi, Machiko Shimmura-Tomita, Toshikatsu Kaburaki, Suguru Nakagawa |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 55581 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |