Diagnostic gaps in light microscopy for malaria case management and control in Dilla Zuria Health Facility, southern Ethiopia
Alayu Bogale, Samuel Tefera, Asaye Mitiku, Zerihun Solomon, Tadesse Misganaw · 2026
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Description
Bogale, Tefera, Mitiku, Solomon, and Misganaw audit malaria slide reading against DNA testing in Ethiopia. Their 2026 paper examines case finding at Dilla Zuria Health Facility. Malaria treatment depends on reading blood smears under microscopes. Wrong reads mean wrong drugs and continued spread. The team checked 474 cases against qPCR.
qPCR detects parasite DNA and served as the reference standard. Among microscopy-positive cases, about a quarter disagreed with qPCR. Nearly one in five microscopy-negative cases was actually positive. Misses clustered in low-density and mixed-species infections. Falciparum calls disagreed in about twenty-one percent of cases. Vivax disagreements ran higher, near twenty-eight percent. Mixed infections fared worst at roughly thirty-five percent. Some misses reflect infections too faint to see. Poorly prepared or misread smears explain others. The authors call for structured, repeated staff training. Quality assurance systems need strengthening alongside. Accuracy shapes control efforts directly.
Catalog record
| CREATOR | Alayu Bogale, Samuel Tefera, Asaye Mitiku, Zerihun Solomon, Tadesse Misganaw |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 38 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |