Exploratory seminal plasma metabolomics and independent HPLC–UV evaluation in men with impaired semen quality
Jiale Xu, Li Guo, Lingxiao Xiong, Jun Li, Peiqiang Wu, Yanmin Ma, Juan Yang, Yuefeng Du · 2026
Read Exploratory seminal plasma metabolomics and independent HPLC–UV evaluation in men with impaired semen quality by Jiale Xu, Li Guo, Lingxiao Xiong, Jun Li, Peiqiang Wu, Yanmin Ma, Juan Yang, Yuefeng Du (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13549830.txt.
Description
Xu and co-authors search the fluid around sperm for chemical clues to poor semen quality in men. Weak semen can combine low counts, poor swimming, odd shapes, and damaged DNA. What changes in seminal plasma alongside those faults was not well mapped. The team ran a broad chemical scan on samples from 10 men with poor semen and 9 with normal semen. Candidate signals were screened by strength and size of change.
Two compounds, cytidine and a small acid, got a second check with a targeted method. The team linked chemical patterns to semen measures and pathways. Public datasets offered a further point of comparison. The work is exploratory and seeks candidate markers for male fertility testing.
Catalog record
| CREATOR | Jiale Xu, Li Guo, Lingxiao Xiong, Jun Li, Peiqiang Wu, Yanmin Ma, Juan Yang, Yuefeng Du |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 69 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |