Clinical and Demographic Factors Associated With Hemorrhagic Transformation Subtypes After Endovascular Thrombectomy for Acute Ischemic Stroke

Nicole Khezri, Marie K. Luff, Salvador Miralbés, Bharath Naravetla, Alejandro Spiotta, Christian Loehr, Mario Martínez-Galdámez, Ryan McTaggart, Luc Defreyne, Pedro Vega, Osama O. Zaidat, Lori Lyn Price, Rishi Gupta, Markus Möhlenbruch, David S. Liebeskind · 2026

Read Clinical and Demographic Factors Associated With Hemorrhagic Transformation Subtypes After Endovascular Thrombectomy for Acute Ischemic Stroke by Nicole Khezri, Marie K. Luff, Salvador Miralbés, Bharath Naravetla, Alejandro Spiotta, Christian Loehr, Mario Martínez-Galdámez, Ryan McTaggart, Luc Defreyne, Pedro Vega, Osama O. Zaidat, Lori Lyn Price, Rishi Gupta, Markus Möhlenbruch, David S. Liebeskind (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13549625.txt.

Description

Nicole Khezri and colleagues identify who bleeds into damaged brain tissue after a clot-removal procedure for stroke, in a 2026 global registry study. Hemorrhagic transformation worsens outcomes after thrombectomy, and its subtypes behave differently. The team analyzed 1,453 patients with blocked front-brain arteries treated in a first-pass device registry, comparing scans a day after treatment and modeling risk factors for each bleeding pattern.

Four in ten patients showed some bleeding on imaging, though only a small share, just over three percent, had symptoms from it. Diabetes, severe stroke scores, and high blood sugar at arrival raised the overall risk, while a healthy early scan score and having atrial fibrillation lowered it. Specific scan and sugar patterns predicted particular subtypes. The authors urge trials to report bleeding by subtype, since lumping them hides who is truly at risk.

Catalog record

CREATORNicole Khezri, Marie K. Luff, Salvador Miralbés, Bharath Naravetla, Alejandro Spiotta, Christian Loehr, Mario Martínez-Galdámez, Ryan McTaggart, Luc Defreyne, Pedro Vega, Osama O. Zaidat, Lori Lyn Price, Rishi Gupta, Markus Möhlenbruch, David S. Liebeskind
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE29008
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13549625

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