Targeting Inflammation–Oxidative Stress Crosstalk: Advances and Challenges in Nanocarrier-Based Interventional Strategies for Pulmonary Arterial Hypertension
Siyuan Song, Jing Wu, Mengyuan Yin, Yuanping Shi · 2026
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Description
Siyuan Song and co-authors review nanocarriers for pulmonary arterial hypertension in a 2026 paper. In this disease, lung artery pressure climbs from hidden beginnings toward heart failure and sudden death. Inflammation and oxidative stress drive much of the damage.
Drugs against those forces suffer from poor solubility, short life, and stray side effects. Tiny carriers such as liposomes, polymers, and exosomes can shield drugs, aim them at lung lesions, and stretch their action. Inhaled delivery piles drug into the lungs while sparing the body. The review lists translation hurdles honestly, from fast lung clearance to shaky production yields and unknown long-term safety.
Catalog record
| CREATOR | Siyuan Song, Jing Wu, Mengyuan Yin, Yuanping Shi |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 71 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |