Elevated Markers of Intestinal Barrier Dysfunction and TLR2 Ligands in Individuals with Type 1 Diabetes
Nafeesah Noorwali, Raphaela Staltner, Aleksejs Fedulovs, Jana Schneider, Polina Zalizko, Andris Romašovs, Ina Bergheim, Jeļizaveta Sokolovska · 2026
Read Elevated Markers of Intestinal Barrier Dysfunction and TLR2 Ligands in Individuals with Type 1 Diabetes by Nafeesah Noorwali, Raphaela Staltner, Aleksejs Fedulovs, Jana Schneider, Polina Zalizko, Andris Romašovs, Ina Bergheim, Jeļizaveta Sokolovska (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13549188.txt.
Description
Nafeesah Noorwali and co-authors test, in a 2026 study, whether the gut barrier leaks in type 1 diabetes and lets bacterial products from Gram-positive germs slip into the blood. A leaky gut is already suspected of fueling the inflammation seen in this disease. Blood from nineteen patients and eighteen matched controls was checked for barrier and exposure markers.
A marker of gut cell damage ran higher in patients, as did the bacterial products and a companion protein. Statistical modeling tied the diabetes itself to the higher bacterial product levels, apart from weight or blood sugar. The authors argue the leak involves more than the classic endotoxin route.
Catalog record
| CREATOR | Nafeesah Noorwali, Raphaela Staltner, Aleksejs Fedulovs, Jana Schneider, Polina Zalizko, Andris Romašovs, Ina Bergheim, Jeļizaveta Sokolovska |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 22 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |