Spathodea campanulata extract as an endodontic irrigant against Enterococcus faecalis: an in vitro and ex vivo study

Jorge Miguel Santacruz-Monzon, Rubén Abraham Domínguez-Pérez, Bertha Fenton-Navarro · 2026

Read Spathodea campanulata extract as an endodontic irrigant against Enterococcus faecalis: an in vitro and ex vivo study by Jorge Miguel Santacruz-Monzon, Rubén Abraham Domínguez-Pérez, Bertha Fenton-Navarro (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13548585.txt.

Description

Jorge Miguel Santacruz-Monzon and colleagues test leaf extracts from the African tulip tree as a rinse for infected root canals, in a 2026 laboratory study. The target bacterium, Enterococcus faecalis, survives inside teeth and resists standard treatment, so plant-based alternatives interest dentists. Six extracts made with different solvents were screened for the lowest doses that stop or kill the bacterium, then compared in dishes against bleach solution.

The water-based extract failed, while the others halted the bacterium at low concentrations. Ethanol and acetone extracts matched the bleach in dish tests at high strength. In extracted human teeth carrying four-week-old bacterial films, the ethanol extract cut living bacteria far more than the bleach rinse did. Rich plant compounds such as flavonoids and tannins may explain the effect, the authors suggest.

Catalog record

CREATORJorge Miguel Santacruz-Monzon, Rubén Abraham Domínguez-Pérez, Bertha Fenton-Navarro
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE31306
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13548585

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