Impact of origin and frequency of premature ventricular complexes on cardiac remodeling: a systematic review and meta-analysis
Gege Zhang, Juan Yao, Jie Gao, Jianfeng Yan, Li Xu, Yining Yang · 2026
Read Impact of origin and frequency of premature ventricular complexes on cardiac remodeling: a systematic review and meta-analysis by Gege Zhang, Juan Yao, Jie Gao, Jianfeng Yan, Li Xu, Yining Yang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13548556.txt.
Description
Gege Zhang and colleagues pool studies on whether extra early heartbeats reshape the heart, in a 2026 systematic review and meta-analysis. Premature ventricular complexes are common and often harmless, yet frequent ones may weaken the heart over time. The team searched four databases for observational studies linking how often these beats occur, or where in the heart they start, to ultrasound measures of heart size and function.
Nine studies with close to nineteen hundred patients qualified. Frequent extra beats went with a weaker pumping fraction and larger heart chambers, including a wider upper chamber. Where the beats originated showed no clear link to pumping strength or chamber size, though only three studies addressed origin. The authors argue that beat frequency matters most when judging risk and timing treatment, while calling the origin evidence too thin for firm conclusions.
Catalog record
| CREATOR | Gege Zhang, Juan Yao, Jie Gao, Jianfeng Yan, Li Xu, Yining Yang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32381 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |