Prevotella melaninogenica Alleviate Mycoplasma pneumoniae Infection Through the Butyrate Based on Multi‐Omic Analysis and Experimental Validation
Zhengyang Xue, Huiliang Xu, Ling Zhu, DeYu Zhao · 2026
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Description
Zhengyang Xue, Huiliang Xu, Ling Zhu, and Deyu Zhao study a lung bacterium that may soften pneumonia in 2026. A wall-less germ is a leading cause of atypical pneumonia in children, and lung microbe data for it were scarce. Two patient groups were profiled at genus and species depth.
One mouth-and-gut bacterium stood out as enriched in the sickest children. Its fat-making pathway was also enriched, and host genes near it pointed to immune control. In mice, pretreatment with the bacterium or its product, butyrate, cut lung inflammation and germ load. The authors propose it as a protective player worth further study.
Catalog record
| CREATOR | Zhengyang Xue, Huiliang Xu, Ling Zhu, DeYu Zhao |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 37 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |