Interaction of nanoplastics with platelets: activation and fibrin clot formation
A. Trostchansky, M. Alarcón · 2026
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Description
Trostchansky and Alarcón studied what happens when tiny plastic particles meet human blood platelets, the cell fragments that drive clotting. Plastic particles have been found in human blood and vessel walls, but their direct effect on blood cells was unclear. The pair exposed platelets to polystyrene particles one hundred nanometers wide, a size that circulates freely, and watched uptake and activation under microscopes and flow instruments.
Platelets grabbed the particles within minutes. The exposure switched platelets on, reshaping their skeletons and releasing granule contents at levels matching a natural clotting trigger. In whole blood the particles promoted dense fibrin networks and became embedded in the clots. The authors warn that circulating plastic may quietly raise clotting risk.
Catalog record
| CREATOR | A. Trostchansky, M. Alarcón |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 27 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |