Early life sugar rationing and ageing related diseases, biological ageing and mortality

Jiazhen Zheng, Zhen Zhou, Jinghan Huang, Qiang Tu, Haisheng Wu, Quan Yang, Qi Qi, Wenbo Huang, Qingwen Ren, Junchun Shen, Xinlong Shi, Can Chen, Chuang Yang, Daniel J Cuthbertson · 2026

Read Early life sugar rationing and ageing related diseases, biological ageing and mortality by Jiazhen Zheng, Zhen Zhou, Jinghan Huang, Qiang Tu, Haisheng Wu, Quan Yang, Qi Qi, Wenbo Huang, Qingwen Ren, Junchun Shen, Xinlong Shi, Can Chen, Chuang Yang, Daniel J Cuthbertson (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13547371.txt.

Description

Zheng and colleagues used Britain's postwar sugar rationing in 2026 as a natural experiment on how the first thousand days of life shape aging. Human proof that early nutrition steers lifelong health is scarce, since such trials cannot be run. Rationing ended in 1953, so people conceived just before and just after differ mainly in early sugar exposure. The study covered about sixty-five thousand UK Biobank participants.

Those exposed to rationing developed hallmark aging diseases about nine percent less often. Their risk of death from any cause ran about nineteen percent lower. By several biological age clocks they measured one to just over one year younger, with lungs, heart, and liver looking youngest. Blood protein patterns fit the picture. The authors say the results back current advice to limit added sugar in infancy.

Catalog record

CREATORJiazhen Zheng, Zhen Zhou, Jinghan Huang, Qiang Tu, Haisheng Wu, Quan Yang, Qi Qi, Wenbo Huang, Qingwen Ren, Junchun Shen, Xinlong Shi, Can Chen, Chuang Yang, Daniel J Cuthbertson
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE53 KB
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13547371

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