Sarcomatoid adrenocortical carcinoma with aggressive disease course: a rare case report and literature review
Xin-Xin Xu, Guang-Fu Zhou, Cheng-Zhou Du, Xiao-Xin Gao, Xiao-Wei Guo, Ya-Long Li, Meng-Yuan Lu, Tian-Xiao He, Peng Chen, Hong-Tao Li · 2026
Read Sarcomatoid adrenocortical carcinoma with aggressive disease course: a rare case report and literature review by Xin-Xin Xu, Guang-Fu Zhou, Cheng-Zhou Du, Xiao-Xin Gao, Xiao-Wei Guo, Ya-Long Li, Meng-Yuan Lu, Tian-Xiao He, Peng Chen, Hong-Tao Li (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13547204.txt.
Description
Xin-Xin Xu and colleagues reported in 2026 an extremely rare and aggressive adrenal gland tumor, sarcomatoid adrenocortical carcinoma, of which only 38 cases have ever been published. A 60-year-old woman came to hospital with an upper abdominal mass. Imaging showed a mixed solid and fluid growth in the space behind the abdomen, suspected to arise from the adrenal cortex. Because the disease was advancing quickly and the patient wanted prompt surgery, hormone tests were skipped.
Surgeons removed the whole tumor, and pathology confirmed the rare diagnosis, with about 60 percent ordinary cancer tissue and 40 percent high-grade sarcoma-like tissue, plus dead areas and tumor in blood vessels. Within a month the cancer had spread across the abdomen, and she died 42 days after surgery. The authors review the few known cases and the open question of drug treatment.
Catalog record
| CREATOR | Xin-Xin Xu, Guang-Fu Zhou, Cheng-Zhou Du, Xiao-Xin Gao, Xiao-Wei Guo, Ya-Long Li, Meng-Yuan Lu, Tian-Xiao He, Peng Chen, Hong-Tao Li |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 23652 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |