Evaluation of the efficacy of a Propionibacterium extract gel in wound healing and symptom relief after open excisional hemorrhoidectomy: a randomized clinical study

S Deidda, C Eberspacher, V Argiolas, L Ventrone, A Testa, S Ascanelli, E Rossin, G Lisi, D Mascagni, L Zorcolo · 2026

Read Evaluation of the efficacy of a Propionibacterium extract gel in wound healing and symptom relief after open excisional hemorrhoidectomy: a randomized clinical study by S Deidda, C Eberspacher, V Argiolas, L Ventrone, A Testa, S Ascanelli, E Rossin, G Lisi, D Mascagni, L Zorcolo (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13547177.txt.

Description

S Deidda and a multicenter team ran a 2026 randomized trial comparing two gels for wounds after open hemorrhoid surgery, a procedure known for painful recovery. One hundred nineteen patients received either a gel made from a bacterial extract or a standard ointment combining hyaluronic acid and silver sulfadiazine. Healing was graded by how much new skin covered the wound, and patients scored pain, burning, and itching over 40 days.

Both products eased pain similarly. Yet the bacterial extract gel healed wounds faster, with complete healing in about 85 percent of its patients by day 40, against about 52 percent for the ointment. Burning and itching also eased more, and satisfaction was far higher, with no reported side effects.

Catalog record

CREATORS Deidda, C Eberspacher, V Argiolas, L Ventrone, A Testa, S Ascanelli, E Rossin, G Lisi, D Mascagni, L Zorcolo
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE37336
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13547177

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