Diversion proctitis during staged restorative proctocolectomy with ileal pouch anal anastomosis is not associated with subsequent cuffitis
Ishaan Dharia, Michael Plietz, Sue Hahn, Sergey Khaitov, Patricia Sylla, Alexander Greenstein, Marla C Dubinsky, Maia Kayal · 2026
Read Diversion proctitis during staged restorative proctocolectomy with ileal pouch anal anastomosis is not associated with subsequent cuffitis by Ishaan Dharia, Michael Plietz, Sue Hahn, Sergey Khaitov, Patricia Sylla, Alexander Greenstein, Marla C Dubinsky, Maia Kayal (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13547168.txt.
Description
Ishaan Dharia and co-authors asked in 2026 whether inflammation of the defunctioned rectum during staged colon surgery predicts later inflammation of the small cuff of tissue left at the pouch join. Their review covered 281 patients with ulcerative colitis who had a three-stage pouch operation at one hospital between 2008 and 2020, all with at least one later pouch examination.
About a quarter showed diversion proctitis, the inflammation in question, on the removed rectum specimen. Those patients needed rectal treatment between stages more often than others. Rates of later cuff inflammation, the main outcome, were statistically indistinguishable between the groups, at roughly 19 percent against 14 percent. The authors conclude the early inflammation signals treatment need but not later cuff trouble.
Catalog record
| CREATOR | Ishaan Dharia, Michael Plietz, Sue Hahn, Sergey Khaitov, Patricia Sylla, Alexander Greenstein, Marla C Dubinsky, Maia Kayal |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 15216 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |