KIT mutation and AHN-associated oncogenic profiles in systemic mastocytosis with an associated hematological neoplasm∗
Paula Navarro-Navarro, Carlos M Fernández-Giménez, Andrés C García-Montero, Iván Álvarez-Twose, Laura Sánchez-Muñoz, Ana Henriques, Alba Pérez-Pons, María González-Tablas, Cristina Teodosio, María González-González, Sergio Matarraz, Antonio López, Paloma Barcena, Enrique Colado, Jordi Esteve, Mª Leo · 2026
Read KIT mutation and AHN-associated oncogenic profiles in systemic mastocytosis with an associated hematological neoplasm∗ by Paula Navarro-Navarro, Carlos M Fernández-Giménez, Andrés C García-Montero, Iván Álvarez-Twose, Laura Sánchez-Muñoz, Ana Henriques, Alba Pérez-Pons, María González-Tablas, Cristina Teodosio, María González-González, Sergio Matarraz, Antonio López, Paloma Barcena, Enrique Colado, Jordi Esteve, Mª Leo (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13546896.txt.
Description
Paula Navarro-Navarro and co-authors present a 2026 study of the genetic layering in a rare blood disorder that arrives with a second blood cancer attached. In systemic mastocytosis, rogue mast cells accumulate; in five to fifteen percent of patients a separate haematological neoplasm rides along. Most such patients carry a signature mutation in the KIT gene, plus extra mutations from the companion cancer.
Data on how often each mutation appears, and in which combinations, were scarce. The team profiled the KIT mutation and the wider oncogenic pattern across these patients. The map helps doctors read prognosis and pick treatments that answer both diseases at once.
Catalog record
| CREATOR | Paula Navarro-Navarro, Carlos M Fernández-Giménez, Andrés C García-Montero, Iván Álvarez-Twose, Laura Sánchez-Muñoz, Ana Henriques, Alba Pérez-Pons, María González-Tablas, Cristina Teodosio, María González-González, Sergio Matarraz, Antonio López, Paloma Barcena, Enrique Colado, Jordi Esteve, Mª Leo |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 55 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |