Molecular and histopathological evaluation of intestinal mucosal damage associated with giardiasis in naturally infected lambs
Zeynep Çelik Kenar, Ayşenur Tural Çifçi, Osman Dağar, Nevin Tuzcu, Hüseyin Karacan, Mehmet Tuzcu · 2026
Read Molecular and histopathological evaluation of intestinal mucosal damage associated with giardiasis in naturally infected lambs by Zeynep Çelik Kenar, Ayşenur Tural Çifçi, Osman Dağar, Nevin Tuzcu, Hüseyin Karacan, Mehmet Tuzcu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13546727.txt.
Description
Zeynep Çelik Kenar and co-authors examined in 2026 how the gut parasite Giardia duodenalis damages the small intestine of naturally infected lambs, at both the tissue and gene level. Twenty-four lambs were grouped by damage severity after microscopic review, ranging from uninfected controls to severe cases. Tissue sections were scored for villus shape, surface integrity, inflammation, and blood vessel congestion, while five gut-related genes were measured.
Damage deepened step by step with severity: villi shrank, surfaces broke down, and immune cells crowded the tissue. Two genes tied to repair rose early in mild and moderate cases, while a detoxifying gene fell in worse cases, suggesting fading protection. A sealing gene rose in all infected groups, as if the gut were trying to patch its barrier.
Catalog record
| CREATOR | Zeynep Çelik Kenar, Ayşenur Tural Çifçi, Osman Dağar, Nevin Tuzcu, Hüseyin Karacan, Mehmet Tuzcu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35506 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |