Therapeutic potential of Lactococcus lactis D4 from fermented buffalo milk (Dadiah) against Staphylococcus aureus-induced diarrhea in mice

Ade Sukma, Azura Adawiya, Elsa Badriyya, Najmiatul Fitria · 2026

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Description

Ade Sukma and co-authors tested in 2026 a probiotic bacterium taken from Dadiah, a traditional Indonesian fermented buffalo milk, against diarrhea caused by Staphylococcus aureus in mice. Twenty-five mice were divided among healthy controls, untreated diarrhea controls, an antibiotic group, and two probiotic dosing schedules. The bacterium, Lactococcus lactis D4, was given by mouth for seven days after infection.

Mice on the twice-daily probiotic schedule fared best, losing little body weight and passing firmer stools than untreated animals. The authors describe the strain as a promising ecological alternative to antibiotics, which face growing resistance in this bacterium. They also frame the work as support for developing local fermented foods into health products.

Catalog record

CREATORAde Sukma, Azura Adawiya, Elsa Badriyya, Najmiatul Fitria
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE20857
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13546716

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