6-Gingerol Regulates the Exosomal miR-148b-3p/ACSL4/Ferroptosis Axis in an in vitro Model of Diabetic Retinopathy
Shuang Liu, Juan Ye, Long Suo, Tao Xu, Yiyi Chen, Wei Liu · 2026
Read 6-Gingerol Regulates the Exosomal miR-148b-3p/ACSL4/Ferroptosis Axis in an in vitro Model of Diabetic Retinopathy by Shuang Liu, Juan Ye, Long Suo, Tao Xu, Yiyi Chen, Wei Liu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13546633.txt.
Description
Shuang Liu and co-authors test a ginger compound in a cell model of diabetic eye disease, in a study from 2026. The disease is a leading cause of blindness and is driven in part by a form of cell death called ferroptosis, which is tied to iron and fat damage. The compound is known to fight such damage, but its role here was untested.
The team grew human eye vessel cells in high sugar, with and without the compound. The compound cut fat damage and iron buildup and raised a key guard protein. It also restored a small RNA, carried in tiny cell parcels, that had fallen under high sugar. That RNA directly targets a gene that drives the cell death path, and blocking steps in the path confirmed the chain.
Catalog record
| CREATOR | Shuang Liu, Juan Ye, Long Suo, Tao Xu, Yiyi Chen, Wei Liu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 38 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |